Cognitive functioning in post‐polio patients with and without general fatigue
Issue: Volume 37, Issue 3, May 2005
Pages: 147-151
DOI: 10.1080/16501970410024172
Abstract:
Objective and design: This study examined 2 main hypotheses. First, whether patients with post-polio suffering from general fatigue (n=10) demonstrate cognitive deficits compared with patients with post-polio without general fatigue (n=10). Secondly, by systematically varied test order administration we examined whether such differences varied as a function of increasing cognitive load during cognitive testing.Subjects: Twenty patients diagnosed with post-polio syndrome, 10 with general fatigue and 10 without fatigue.Results: Neither of the 2 hypotheses were confirmed. The group with general fatigue reported elevated levels of depression. However, no systematic association between level of depression and cognitive performance could be detected.Conclusion: The results of this study provide no evidence that general fatigue or cognitive load affects cognitive functioning in post-polio.
Authors:
Gunilla Östlund A1, A3, Kristian Borg A1, A3, Åke Wahlin A2, A4
A1 Department of Public Health Science, Karolinska Institutet
A2 Stockholm Gerontology Research Centre and Division of Geriatric Epidemiology, Karolinska Institutet
A3 Department of Rehabilitation Medicine at, Huddinge University Hospital
A4 Department of Psychology, Stockholm University, Stockholm, Sweden
Key words:
post‐polio, fatigue, cognition
References:
- Dalakas, MC.The post‐polio syndrome as an evolved clinical entity 1995; 25: 68–80 Definition and clinical description. Ann NY Acad Sci
- Grafman, J, Clark, K, Richardson, D, Dinsmore, S, Stein, D, Dalakas, MC.Neuropsychology of post‐polio syndrome 1995; 25: 103–110 Ann NY Acad Sci
- Ahlström, G, Gunnarsson, LG, Leissner, P, Sjödén, P‐O.Epidemiology of neuromuscular diseases, including the postpolio sequelae, in a Swedish county 1993; 12: 262–269 Neuroepidemiology
- Borg, K.Post‐polio fatigue. In: 2004, pp; 77–86 Silver JK, Gawne AC, edsPost‐polio syndromeState of the arts review
- Berlly, MH, Strauser, WW, Hall, KM.Fatigue in postpolio syndrome 1991; 72: 115–118 Arch Phys Med Rehabil
- Bruno, RL, Cohen, JM, Galski, T, Frick, NM.The neuroanatomy of post‐polio fatigue 1994; 75: 498–504 Arch Phys Med Rehabil
- Schanke, AK.Psychological distress, social support and coping behaviour among polio survivors: a 5 year perspective on 63 polio patients 1997; 3: 108–116 Disabil Rehabil
- Schanke, AK, Stanghelle, JK.Fatigue in polio survivors 2000; 39: 243–251 Spinal Cord
- Stein, DP, Dambrosia, JM, Dalakas, MC.A double‐blind, placebo‐controlled trial of amantadine for the treatment of fatigue in patients with the post‐polio syndrome 1995; 25: 296–302 Ann NY Acad Sci
- Packer, TL, Sauriol, A, Brouwer, B.Fatigue secondary to chronic illness: postpolio syndrome, chronic fatigue syndrome, and multiple sclerosis 1994; 75: 1122–1126 Arch Phys Med Rehabil
- Bruno, RL, Galski, T, DeLuca, J.The neuropsychology of post‐polio fatigue 1993; 74: 1061–1065 Arch Phys Med Rehabil
- Bruno, RL, Sapolsky, R, Zimmermann, JR, Frick, NM.Pathophysiology of a central cause of post‐polio fatigue 1995; 753: 257–275 Ann NY Acad Sci
- Kantowitz, BH, Roediger, HL.1978; Experimental psychology
- Hazendonk, KM, Crowe, SF.A neuropsychological study of the postpolio syndrome: support for depression without neuropsychological impairment 2000; 3: 112–118 Neuropsych Neuropsychol Behav Neurol
- Schanke, AK, Stanghelle, JK, Andersson, S, Ophelm, A, Ström, V, Solbakk, A‐K.Mild versus severe fatigue in polio survivors: special characteristics 2000; 34: 134–140 J Rehabil Med
- Degl′Innocenti, A, Ågren, H, Bäckman, L.Executive deficits in major depression 1998; 97: 182–183 Acta Psychiatr Scand
- Ravnkilde, B, Videbech, P, Clemmensen, K, Egander, A, Rasmussen, NA, Rosenberg, R.Cognitive deficits in major depression 2000; 3: 239–251 Scand J Psychol
- Dick, B, Eccleston, C, Crombez, G.Attention functioning in fibromyalgia, rheumatoid arthritis, and musculoskeletal pain patients 2002; 47: 639–644 Arthritis Rheum
- Grisart, JM, Van der Linden, M.Conscious and automatic uses of memory in chronic pain patients 2001; 94: 305–313 Pain
- Halstead, LS, Gawne, AC, Pham, BT.National rehabilitation hospital limb classification for exercise, research, and clinical trials in post‐polio patients 1995; 753: 343–353 Ann NY Academ Sci
- Halstead, LS, Rossi, CD.Post‐polio syndrome: clinical experience with 132 consecutive outpatients. In: 1987, pp; 13–23 Halstead LS, Wiechers DO, edsResearch and clinical aspects of the late effects of poliomyelitis
- Thorén‐Jönsson, A‐L, Hedberg, M, Grimby, G.Distress in everyday life in people with poliomyelitis sequelae 2001; 33: 119–127 J Rehabil Med
- Beck, AT, Steer, RA.Becks Depression Inventory – BDI 1996
- Bäckman, L, Small, BJ, Wahlin, Å.Aging and memory: cognitive and biological perspectives. In: 2001, pp; 349–377 Birren JE, Schaie KW, edsHandbook of the psychology of aging (5th ed)
- Spreen, O, Strauss, E.A compendium of neuropsychological tests 1991
- Lezak, M.Neuropsychological Assessment 1995; 3rd edn
- Reitan, RM, Davidson, LA.Clinical neuropsychology: current status and applications 1974
- Diller, L, Ben‐Yishay, Y, Gerstman, LJ, Goodin, R, Gordon, W, Weinberg, J.1974; Studies in cognition and rehabilitation in hemiplegia. Rehabilitation monograph No. 50. New York:
- Wahlin, Å, Bäckman, L, Winblad, B.Free recall and recognition of slowly and rapidly presented words in very old age: a community‐based study 1995; 21: 251–271 Exp Aging Res
- Bäckman, L, Wahlin, Å.Influences of item organizability and semantic retrieval cues on word recall in very old age 1995; 2: 312–325 Aging Cognit
- Wechsler, D.1981; Manual for the Wechsler Adult Intelligence Scale Revised
- Vanderberg, SG.1971; Mental Rotation Test Institute for Behavioural Genetics
- Nilsson, LG, Bäckman, L, Erngrund, K, Nyberg, L, Adolfsson, R, Bucht, G, et al.The Betula Prospective Cohort study: memory, health, and aging 1997; 4: 1–32 Aging Neuropsychol Cogn
- Bruno, RL, Zimmermann, JR.Word finding difficulty as a post‐polio sequelae 2000; 79: 343–348 Am J Phys Med Rehabil
- Horemans, HL, Nollet, F, Beelen, A, Lankhorst, GJ.A comparison of 4 questionnaires to measure fatigue in postpoliomyelitis syndrome 2004; 85: 392–398 Arch Phys Med Rehabil